Average-Weight Methodology in Weight-Based Unfractionated Heparin Therapy in the Presence of Obesity
نویسندگان
چکیده
منابع مشابه
The use of average body weight in dosing unfractionated heparin.
Correspondence Since no exact threshold accurately predicts an outcome or obligates specifi c management, any selection of cutoffs is arbitrary, whether based on fraction of the hemithorax or actual volume. Separation into thirds 2 or use of quartiles, as suggested by Drs Hu and Zhong, are both, to our knowledge, without precedent. We designed our cutoffs rationally, with no a priori assumption...
متن کاملUnfractionated and low molecular weight heparin
Background Unfractionated heparin (UFH) is mostly obtained from porcine and bovine mucosa and has been widely used for the treatment and prevention of thrombotic events. It consists of molecular chains of various lengths varying from 2000 to 40,000 Da [1]. Low molecular weight heparins (LMWHs) are smaller chains of UFH that can be obtained, from unfractionated heparin, by various chemical and e...
متن کاملLow molecular weight heparin versus unfractionated heparin in the initial treatment of venous thromboembolism.
In this review, we analyze data from randomized trials in which low molecular weight heparin was compared with unfractionated heparin, both to estimate the treatment effect of low molecular weight heparin in the initial treatment of venous thromboembolism and to evaluate the effect of the varied proportion of included cancer patients (6% to 22.7%) on the incidence of outcome events (recurrence ...
متن کاملCost-effectiveness of low-molecular-weight heparin and unfractionated heparin in treatment of deep vein thrombosis.
BACKGROUND Acute deep vein thrombosis has traditionally been treated with unfractionated heparin (UFH), administered intravenously, but low-molecular-weight heparins (LMWH), administered subcutaneously, have recently become available. The authors sought to determine which therapy was more cost-effective for inpatient and outpatient treatment of deep vein thrombosis. METHODS An incremental cos...
متن کاملEffect of switching unfractionated heparin to low-molecular-weight heparin on serum potassium in hemodialysis patients.
INTRODUCTION Unfractionated (UF) heparin is the most common anticoagulant used during hemodialysis. Failure of the kidneys to excrete potassium as well as heparin-induced reduction of aldosterone synthesis put hemodialysis patients at risk of hyperkalemia. It has not yet been clearly known whether hyperkalemia is also induced by low-molecular-weight (LMW) heparins. This study aimed to evaluate ...
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ژورنال
عنوان ژورنال: Chest
سال: 2017
ISSN: 0012-3692
DOI: 10.1016/j.chest.2016.12.016